Professor, Senior Scientist and Director of Life Science Alliance
European Molecular Biology Laboratory and
Stanford University
SCIENTIFIC VITA
| 1994 – 1997 | Bachelor of Science (summa cum laude) Molecular Biophysics and Biochemistry Yale University, New Haven |
| 1997 – 2001 | Ph.D. Department of Genetics Stanford University School of Medicine, Stanford |
| 2003 – 2013 | Group Leader (Visiting) Stanford Genome Technology Center Stanford University |
| Since 2003 | Group Leader Genome Biology Unit European Molecular Biology Laboratory (EMBL) |
| 2009 – 2016 | Founding Joint Head of the Genome Biology Unit (2013-2016, Associate Head) European Molecular Biology Laboratory (EMBL) |
| Since 2009 | Senior Scientist European Molecular Biology Laboratory (EMBL) |
| Since 2013 | Professor of Genetics Stanford University |
| Since 2013 | Co-Director Stanford Genome Technology Center Stanford University |
| Since 2014 | Director, Life Science Alliance A Stanford-EMBL collaboration |
| Since 2016 | Member Stanford Cardiovascular Institute Stanford University School of Medicine |
AWARDS
| 1998 – 2001 | Howard Hughes Predoctoral Fellow |
| 2004 – 2010 | Emmy Noether-Program Young Investigator Deutsche Forschungsgemeinschaft |
| 2012 | ERC Advanced Invetigator |
| 2016 | Ira Herskowitz Award Genetics Society of America |
| 2017 | ERC Advanced Invetigator |
SCIENTIFIC COORDINATION
| Since 2010 | Supervisory Board EMBL Enterprise Management Technology Transfer GmbH, Heidelberg |
| Since 2010 | President of Scientific Advisory Consultant, Sophia Genetics, Lausanne |
| Since 2013 | Director of Graduate Admissions Department of Genetics, Stanford |
| Since 2016 | Scientific Advisory Board EMBL-GSK Partnership |
| Since 2017 | Board of Directors, Levitas, California, USA |
| Since 2017 | Life Science Advisory Board LAM Research, California, USA |
| Since 2018 | Scientific Advisory Board Bio-Med Big Data Center Shanghai Institute for Biological Sciences |
RELEVANT PUBLICATIONS
Inhibition of NGLY1 Inactivates the Transcription Factor Nrf1 and Potentiates Proteasome Inhibitor Cytotoxicity. Tomlin FM, Gerling-Driessen UIM, Liu YC, Flynn RA, Vangala JR, Lentz CS, Clauder-Muenster S, Jakob P, Mueller WF, Ordoñez-Rueda D, Paulsen M, Matsui N, Foley D, Rafalko A, Suzuki T, Bogyo M, Steinmetz LM, Radhakrishnan SK, Bertozzi CR. ACS Cent Sci. 2017 Nov 22;3(11):1143-1155. doi: 10.1021/acscentsci.7b00224. Epub 2017 Oct 25
Human haematopoietic stem cell lineage commitment is a continuous process. Velten L, Haas SF, Raffel S, Blaszkiewicz S, Islam S, Hennig BP, Hirche C, Lutz C, Buss EC, Nowak D, Boch T, Hofmann WK, Ho AD, Huber W, Trumpp A, Essers MA, Steinmetz LM. Nat Cell Biol. 2017 Apr;19(4):271-281. doi: 10.1038/ncb3493. Epub 2017 Mar 20.
Single-cell transcriptome analysis reveals coordinated ectopic gene-expression patterns in medullary thymic epithelial cells. Brennecke P, Reyes A, Pinto S, Rattay K, Nguyen M, Küchler R, Huber W, Kyewski B, Steinmetz LM. Nat Immunol. 2015 Sep;16(9):933-41. doi: 10.1038/ni.3246. Epub 2015 Aug 3.
Widespread Co-translational RNA Decay Reveals Ribosome Dynamics. Pelechano V, Wei W, Steinmetz LM. Cell. 2015 Jun 4;161(6):1400-12. doi: 10.1016/j.cell.2015.05.008.
Mitochondrial protein sorting as a therapeutic target for ATP synthase disorders. Aiyar RS, Bohnert M, Duvezin-Caubet S, Voisset C, Gagneur J, Fritsch ES, Couplan E, von der Malsburg K, Funaya C, Soubigou F, Courtin F, Suresh S, Kucharczyk R, Evrard J, Antony C, St Onge RP, Blondel M, di Rago JP, van der Laan M, Steinmetz LM. Nat Commun. 2014 Dec 18;5:5585. doi: 10.1038/ncomms6585.