Prof. Dr. med. Benjamin Meder, Co-Coordinator

Deputy Medical Director, Department of Cardiology, Angiology, Pneumology
University Hospital Heidelberg

Head Genomic Research & Institute for Cardiomyopathies Heidelberg
University Hospital Heidelberg

 

SCIENTIFIC VITA

1998 – 2005 Medical School,
Albert-Ludwigs-University of Freiburg
2001 – 2004 Research Doctorate, Department of Cardiology, University Hospital of Freiburg
2003 – 2004 Scientific Assistant, Laboratory of Engineering & Bioinformatics, Perfusion Technologies GmbH
2005 – 2009 Research Fellow, Heidelberg University
Since 2009 Research Group Leader, Laboratory of Molecular Genetics and Translational Biotechnology, Heidelberg
Since 2011 Head of Genomic Research, Department of Internal Medicine III, University Hospital Heidelberg
Since 2015 Head Institute for Cardiomyopathies Heidelberg (ICH.)
Since 2018 Stanford University School of Medicine, Genome Technology Center, California, USA – Visiting Associate Professor of Genetics
Since 2018 Deputy Medical Director, Department of Cardiology, Angiology, Pneumology
University Hospital Heidelberg

 

AWARDS

2001 – 2005 E-Fellows Scholarship, Munich, Germany
2003 – 2005 Scholarship of Bayer Foundations, Leverkusen, Germany
2009 Best Poster Award, 7th Dutch-German Meeting of the Molecular Cardiology Groups
2010 Winterstein Science Award of the German Heart Foundation
2009 – 2011 Research fellowship Young Investigator Award of the Medical Faculty Heidelberg
2017 Wilhelm P. Winterstein Science Award of the German Heart Foundation
2017 European Society of Cardiology “primus inter pares”

 

SCIENTIFIC COORDINATION

2001 – 2013 Coordinator of the Innovation Alliance Subgenome Fractionation for High-throughput Sequencing, Germany
Since 2013 Coordinator Cardiomyopathy Group DZHK Registries, Germany
Since 2013 Steering Committee of the Network for Congenital Heart Diseases, Germany
Since 2015 Coordinator Cardiomyopathy Research Board
Since 2018 Co-Coordinator “Informatics for Life”

 

PATENTS

US Patent 9,938,580 Epigenetic signatures as marker for cardiomyopathies and myocardial insufficiencies (Granted April 10, 2018). US Patent 9,611,511 Complex miRNA sets as novel biomarkers for an acute coronary syndrome (Granted April 4, 2017). EP 10 004 190.4 Complex miRNA sets as novel biomarkers for an acute coronary syndrome; EP 11715666.1 Complex miRNA sets as novel biomarkers for an acute coronary syndrome; EP 101 851 36.8 Complex miRNS sets as novel biomarkers for an acute coronary syndrome; EP 11169192.9 MicroRNA signatures als Biomarker für die dilatative Kardiomypathie (DCM) und Herzinsuffizienz; PCT/EP2012/060927 Complex set of miRNAs as noninvasive biomarkers for dilated cardiomyopathy; EP12163180.8 Complex sets of miRNAs as non-invasive biomarkers for early diagnosis of acute myocardial infarction; PCT/EP2013/057118 Complex sets of miRNAs as non-invasive biomarkers for early diagnosis of acute myocardial infarction; EP 13168684.2 MICRORNA AS NON-INVASIVE BIOMARKERS FOR HEART FAILURE

 

RELEVANT PUBLICATIONS

Haas J, Mester S, Lai A, Frese KS, Sedaghat-Hamedani F, Kayvanpour E, Rausch T, Nietsch R, Boeckel JN, Carstensen A, Völkers M, Dietrich C, Pils D, Amr A, Holzer DB, Martins Bordalo D, Oehler D, Weis T, Mereles D, Buss S, Riechert E, Wirsz E, Wuerstle M, Korbel JO, Keller A, Katus HA, Posch AE, Meder B. Genomic structural variations lead to dysregulation of important coding and non-coding RNA species in dilated cardiomyopathy. EMBO Mol Med. 2017 Nov 14. pii: e201707838.

Sedaghat-Hamedani F, Haas J, Zhu F, Geier C, Kayvanpour E, Liss M, Lai A, Frese K, Pribe-Wolferts R, Amr A, Li DT, Samani OS, Carstensen A, Bordalo DM, Müller M, Fischer C, Shao J, Wang J, Nie M, Yuan L, Haßfeld S, Schwartz C, Zhou M, Zhou Z, Shu Y, Wang M, Huang K, Zeng Q, Cheng L, Fehlmann T, Ehlermann P, Keller A, Dieterich C, Streckfuß-Bömeke K, Liao Y, Gotthardt M, Katus HA, Meder B. Clinical genetics and outcome of left ventricular non-compaction cardiomyopathy. Eur Heart J. 2017 Oct 6. doi: 10.1093/eurheartj/ehx545.

Meder B, Haas J, Sedaghat-Hamedani F, Kayvanpour E, Frese K, Lai A, Nietsch R, Scheiner C, Mester S, Martins Bordalo D, Amr A, Dietrich C, Pils D, Siede D, Hund H, Bauer AS, Holzer DB, Ruhparwar A, Mueller-Hennessen M, Weichenhan D, Plass C, Weis TM, Backs J, Wuerstle ML, Keller A, Katus HA, Posch AE. Epigenome-Wide Association Study Identifies Cardiac Gene Patterning and A Novel Class of Biomarkers for Heart Failure. Circulation. 2017 Aug 24. doi: 10.1161/CIRCULATIONAHA.117.027355.

Amr A, Kayvanpour E, Sedaghat-Hamedani F, Passerini T, Mihalef V, Lai A, Neumann D, Georgescu B, Buss S, Mereles D, Zitron E, Posch AE, Würstle M, Mansi T, Katus HA, Meder B. Personalized Computer Simulation of Diastolic Function in Heart Failure. Genomics Proteomics Bioinformatics. 2016 Aug;14(4):244-52. doi: 10.1016/j.gpb.2016.04.006.

Kayvanpour E, Mansi T, Sedaghat-Hamedani F, Amr A, Neumann D, Georgescu B, Seegerer P, Kamen A, Haas J, Frese KS, Irawati M, Wirsz E, King V, Buss S, Mereles D, Zitron E, Keller A6, Katus HA, Comaniciu D, Meder B. Towards Personalized Cardiology: Multi-Scale Modeling of the Failing Heart. PLoS One. 2015 Jul 31;10(7):e0134869. doi: 10.1371/journal.pone.0134869.