Head of Molecular and Translational Cardiology Division
W3-Professor for Molecular and Translational Cardiology
University Hospital Heidelberg
SCIENTIFIC VITA
| 1991 – 1998 | Study of Medicine University of Heidelberg and University of Lübeck |
| 1998 – 1999 | Medical Internship University Hospital Lübeck |
| 1999 | Full License to Practice Medicine (Approbation) |
| 1999 – 2002 | Resident Department of Cardiology, Angiology and Pulmonology, University Hospital Lübeck |
| 2002 | Medical Doctorate Degree (summa cum laude) |
| 2002 – 2006 | Resident Department of Cardiology, Angiology and Pulmonology, University Hospital Heidelberg |
| 2003 – 2004 | Post-Doctorate Training Center for Translational Medicine, Thomas Jefferson University, Philadelphia, USA |
| 2006 – 2010 | Assistant Professor and Faculty Member Medical College and Department of Medicine, Thomas Jefferson University Hospital, Philadelphia, USA |
| 2009 | Board Certification |
| Since 2010 | W3-Professor for Molecular and Translational Cardiology Medical College and University Hospital Heidelberg |
| Since 2010 | Adjunct Associate Professor Jefferson Medical College, Thomas Jefferson University, Philadelphia, USA |
BIOINDUSTRIAL CAREER
| 2013 – 2014 | Co-founder and Chief Executive Officer of the Biotech Startup InoCard GmbH |
| 2014 – 2017 | Managing Director of uniQure GmbH Germany (successor to InoCard GmbH and German affiliation of uniQure NV, Amsterdam, Netherlands) |
| 2015 – 2017 | Member of the uniQure NV Leadershipteam and Senior Vice President Cardiovascular Therapeutic Area |
AWARDS
| 2001 | German Society of Cardiology (DGK), of the Oskar Lapp Foundation Science Award |
| 2001 | Trainee Award Council on Basic Cardiovascular Sciences of the American Heart Association (AHA) |
| 2002 | Early Career Development Award Council on Basic Cardiovascular Sciences of the American Heart Association (AHA) |
| 2004 | Young Investigator Award of the German Society for Internal Medicine (GDIM) |
| 2004 | Wilhelm P. Winterstein Science Award of the German Heart Foundation |
| 2004 | Basic Science Award of the German Society for the Prevention and Rehabilitation of Cardiovascular Diseases (DGPR) |
| 2004 | Louis N. and Arnold M. Katz Price Finalist Council on Basic Cardiovascular Sciences of the American Heart Association (AHA), |
| 2007 | W.W. Smith Charitable Trust stipend award |
| 2009 | Innovation Award of BioRegion Germany Association |
| 2010 | ADUMED Science Award, ADUMED Foundation |
| 2013 | Investors’ Choice Award of the Health Axis Europe/BioRN Excellence cluster competition |
| 2015 | German Society of Cardiology Albert-Fränkel Award |
PATENTS
Cardiac power failure treatment (WO2000/02453)
Therapeutic Window S100A1 (PCT/EP13/186913)
Muscle function enhancing peptide (PCT/EP10/002343)
Short peptides for enhancing muscle function (PCT/EP13/880705)
Tissue specific gene therapy treatment (WO2008/054713)
RELEVANT PUBLICATIONS
El-Battrawy I, Zhao Z, Lan H, Li X, Yücel G, Lang S, Sattler K, Schünemann JD, Zimmermann WH, Cyganek L, Utikal J, Wieland T, Bieback K, Bauer R, Ratte A, Pribe-Wolferts R, Rapti K, Nowak D, Wittig J, Thomas D, Most P, Katus HA, Ravens U, Schmidt C, Borggrefe M, Zhou XB, Müller OJ, Akin I. Ion Channel Dysfunctions in Dilated Cardiomyopathy in Limb-Girdle Muscular Dystrophy. Circ Genom Precis Med. 11(3):e001893, 2018
Lehmann LH, Jebessa ZH, Kreusser MM, Horsch A, He T, Kronlage M, Dewenter M, Sramek V, Oehl U, Krebs-Haupenthal J, von der Lieth AH, Schmidt A, Sun Q, Ritterhoff J, Finke D, Völkers M, Jungmann A, Sauer SW, Thiel C, Nickel A, Kohlhaas M, Schäfer M, Sticht C, Maack C, Gretz N, Wagner M, El- Armouche A, Maier LS, Londoño JEC, Meder B, Freichel M, Gröne HJ, Most P, Müller OJ, Herzig S, Furlong EEM, Katus HA, Backs J. A proteolytic fragment of histone deacetylase 4 protects the heart from failure by regulating the hexosamine biosynthetic pathway. Nat Med. 1, 62-72, 2018
Müller I, Vogl T, Pappritz K, Miteva K, Savvatis K, Rohde D, Most P, Lassner D, Pieske B, Kühl U, Van Linthout S, Tschöpe C. Pathogenic Role of the Damage-Associated Molecular Patterns S100A8 and S100A9 in Coxsackievirus B3-Induced Myocarditis. Circ Heart Fail. 11, pii: e004125 2017 .
Kossack M, Hein S, Juergensen L, Siragusa M, Benz A, Katus HA, Most P*, Hassel D. Induction of cardiac dysfunction in developing and adult zebrafish by chronic isoproterenol stimulation. J Mol Cell Cardiol. 108, 95-105, 2017 (*co-corresponding and co-senior author)
Schlegel P, Reinkober J, Meinhardt E, Tscheschner H, Gao E, Schumacher SM, Yuan A, Backs J, Most P, Wieland T, Koch WJ, Katus HA, Raake PW. G protein-coupled receptor kinase 2 promotes cardiac hypertrophy. PLoS One. 12:e0182110, 2017.