Dr. Nagaiah Chamakuri Faculty at the Indian Institute of Science Education and Research (IISER), Thiruvananthapuram, India will give a talk on: "Challenges in Solving Large scale PDE-constrained Optimization" This talk presents a feasible study of optimal control techniques for cardiac defibrillation based on the bidomain-bath equations posed on a rabbit ventricle geometry. The bidomain model consists of a system of elliptic partial differential equations coupled with a non-linear parabolic equation of reaction-diffusion type, where a set